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5020-11603
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Inertsil ODS-3

by GL Sciences

Inertsil ODS-3

  • Virtually perfect peak shape for most bases and acids
  • Predictable selectivity with very low operating pressure making this ideal for fast/LC,UPLCTM, and LC/MS
  • Exceptional physical and chemical durability provides long column life
  • Vast database of chromatographic applications available to assist in method development

GL Sciences’ Inertsil columns offer everything you need for your critical separations in all phases of drug development, and something less. Inertsil’s uniquely modified silicas and meticulously engineered column hardware allow our columns to operate at significantly lower back pressures than competitive columns, without sacrificing efficiency. Inertsil’s wide pH compatibility and excellent stability atelevatedtemperatures make it the ideal choicefor yourchromatographyneeds,whether youare using a traditional HPLC system or the latestrapidgradient LC/MS system with precise temperature control.
Inertsil is available in a wide range of bonded phases, including ODS-3, ODS-Sprint for reduced retention of non-polar compounds, C8-3, Phenyl-3, ODS-EP containing an embedded polar group for increased retention of polar compounds,CN-3, HILIC, NH2, Diol,and a Polymerically bonded ODS-P phase with unique selectivity for planar compounds, uniquely designed for analysis of 16 priority PAHs in environmentalsamples but has also found to be useful for pharmaceutical analysis of planar compounds.
The Inertsil 3-series represents a major advance in performance over the original Inertsil 2-Series. Inertsil 3-Series phases, including ODS-3, ODS-3V, ODS-SPRINT ODS-P, ODS-EP, C8-3, Ph-3, CN-3, NH2, Diol, and SIL-100Å, are based on a purer, higher surface area silica which is specially manufactured to provide maximum bonded phase coverage. The result is a series of columns which provide excellent peak shapes using simple eluents while operating at low pressure.
Inertsil ODS-3, along with most of the other Inertsil 3-series phases, are available in 3, 5, and 8 micron particle sizes in column configurations ranging from capillary to 50mm ID preparative sizes.
Inertsil phases are known to provide excellent results and long column life at pH levels of 9-10. However, optimum column life may be achieved at a pH between 2 and 7.5.

Application areas:
Acidic compounds Basic compounds
Specification
Vendor GL Sciences pH stability from 2.0
Brand Inertsil ODS-3 pH stability to 7.5
Modifification Silica/C18 Max Pressure 2900
Mode Reversed-Phase Surface Area 450
Particle Size Carbon Load, % 15.0
Length Endcapped Yes
Internal Diameter Operating Temperature 60
Pore size 100
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
KNAUER Eurospher II Reversed-Phase Silica/C18 4.0 mm 100 mm 5.0 μm 100 Å On request
Dikma Technologies Inc. Leapsil C18 Reversed-Phase Silica/C18 2.1 mm 250 mm 2.7 μm 100 Å 761.00
Thermo Fisher Scientific Hypesil GOLD Reversed-Phase Silica/C18 10.0 mm 50 mm 12.0 μm 175 Å On request
Thermo Fisher Scientific Hypurity Reversed-Phase Silica/C18 4.6 mm 100 mm 5.0 μm 190 Å On request
Princeton Chromatography Inc. PrincetonSPHER C18-300 Reversed-Phase Silica/C18 4.6 mm 150 mm 5.0 μm 300 Å On request
Merck Chromolith® Reversed-Phase Silica/C18 4.6 mm 100 mm Monolithic μm 130 Å On request
Welch Materials Topsil C18 Reversed-Phase Silica/C18 3.0 mm 50 mm 3.0 μm 150 Å On request
GL Sciences Inertsil ODS-SP Reversed-Phase Silica/C18 4.0 mm 250 mm 3.0 μm 100 Å On request
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