by GL Sciences
Inertsil ODS-3
GL Sciences’ Inertsil columns offer everything you need for your critical separations in all phases of drug development, and something less. Inertsil’s uniquely modified silicas and meticulously engineered column hardware allow our columns to operate at significantly lower back pressures than competitive columns, without sacrificing efficiency. Inertsil’s wide pH compatibility and excellent stability atelevatedtemperatures make it the ideal choicefor yourchromatographyneeds,whether youare using a traditional HPLC system or the latestrapidgradient LC/MS system with precise temperature control.
Inertsil is available in a wide range of bonded phases, including ODS-3, ODS-Sprint for reduced retention of non-polar compounds, C8-3, Phenyl-3, ODS-EP containing an embedded polar group for increased retention of polar compounds,CN-3, HILIC, NH2, Diol,and a Polymerically bonded ODS-P phase with unique selectivity for planar compounds, uniquely designed for analysis of 16 priority PAHs in environmentalsamples but has also found to be useful for pharmaceutical analysis of planar compounds.
The Inertsil 3-series represents a major advance in performance over the original Inertsil 2-Series. Inertsil 3-Series phases, including ODS-3, ODS-3V, ODS-SPRINT ODS-P, ODS-EP, C8-3, Ph-3, CN-3, NH2, Diol, and SIL-100Å, are based on a purer, higher surface area silica which is specially manufactured to provide maximum bonded phase coverage. The result is a series of columns which provide excellent peak shapes using simple eluents while operating at low pressure.
Inertsil ODS-3, along with most of the other Inertsil 3-series phases, are available in 3, 5, and 8 micron particle sizes in column configurations ranging from capillary to 50mm ID preparative sizes.
Inertsil phases are known to provide excellent results and long column life at pH levels of 9-10. However, optimum column life may be achieved at a pH between 2 and 7.5.
| Vendor | GL Sciences | pH stability from | 2.0 |
| Brand | Inertsil ODS-3 | pH stability to | 7.5 |
| Modifification | Silica/C18 | Max Pressure | 2900 |
| Mode | Reversed-Phase | Surface Area | 450 |
| Particle Size | Carbon Load, % | 15.0 | |
| Length | Endcapped | Yes | |
| Internal Diameter | Operating Temperature | 60 | |
| Pore size | 100 |
| Vendor | Brand | Mode | Modification | Int. diam. | Length | Particles | Pores | Price |
|---|---|---|---|---|---|---|---|---|
| Higgins Analytical | CLIPEUS C18 | Reversed-Phase | Silica/C18 | 0.3 mm | 150 mm | 5.0 μm | 120 Å | On request |
| Thermo Fisher Scientific | BetaMax | Reversed-Phase | Silica/C18 | 3.0 mm | 30 mm | 5.0 μm | 60 Å | On request |
| ACE | ACE C18-HL | Reversed-Phase | Silica/C18 | 4.0 mm | 125 mm | 5.0 μm | 90 Å | On request |
| Agilent Technologies | Agilent Polaris | Reversed-Phase | Silica/C18 | 2.0 mm | 50 mm | 5.0 μm | 180 Å | On request |
| Varian | Polaris C18-A | Reversed-Phase | Silica/C18 | 3.0 mm | 200 mm | 3.0 μm | 180 Å | On request |
| GL Sciences | Inertsil ODS-SP | Reversed-Phase | Silica/C18 | 0.5 mm | 50 mm | 3.0 μm | 100 Å | On request |
| Sepax Technologies | Sepax GP 120 C18 | Reversed-Phase | Silica/C18 | 21.2 mm | 150 mm | 5.0 μm | 120 Å | On request |
| Welch Materials | Ultisil AQ-C18 | Reversed-Phase | Silica/C18 | 2.1 mm | 200 mm | 3.0 μm | 120 Å | On request |
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