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5020-84914
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Inertsil C8-3

by GL Sciences

Inertsil C8-3

  • Virtually perfect peak shape for most bases and acids
  • Unique selectivity
  • Exceptional physical and chemical durability provides long column life
  • Vast database of chromatographic applications available to assist in method development
  • Very low operating back pressure

Inertsil C8-3 provides pure reverse phase characteristics that are critical to resolving highly polar compounds like acidic and basic pharmaceuticals. The near perfect C8 ( octyl ) phase and end-capping coverage on this material results in symmetric, narrow peaks for even the most polar compounds while using simple eluents like aqueous MeCN or MeOH. The need for ion-pair and competing-amine eluent modifiers that are necessary with many other reverse phase columns is eliminated on Inertsil 3-series phases.
The Inertsil 3-series represents a major advance in performance over the original Inertsil 2-Series. Inertsil 3-Series phases, including ODS-3, ODS-3V, ODS-SPRINT , ODS-P, ODS-EP, Ph-3, CN-3, NH2, Diol, and SIL-100A°, are based on a purer, higher surface area silica which is specially manufactured to provide maximum bonded phase coverage. The result is a series of columns which provide excellent peak shapes using simple eluents while operating at low pressure.
Inertsil phases are known to provide excellent results and long column life at pH levels of 9-10. However, optimum column life may be achieved at a pH between 2 and 7.5.

Application areas:
Acidic compounds Basic compounds
Specification
Vendor GL Sciences Max Pressure 2900
Brand Inertsil C8-3 Surface Area 450
Modifification Silica/C8 Carbon Load, % 9.0
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 2.0
Internal Diameter pH stability to 7.5
Pore size 100
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
ES Industries Chromegabond 500 MC-8 Reversed-Phase Silica/C8 4.6 mm 250 mm 5.0 μm 500 Å On request
Thermo Fisher Scientific Hypesil GOLD Reversed-Phase Silica/C8 0.075 mm 100 mm 5.0 μm 175 Å On request
Imtakt Unison US-C8 Reversed-Phase Silica/C8 6.0 mm 150 mm 5.0 μm 130 Å On request
BISCHOFF ProntoSIL 60-5-C8 SH Reversed-Phase Silica/C8 4.6 mm 125 mm 5.0 μm 60 Å On request
GL Sciences Inertsil C8-4 Reversed-Phase Silica/C8 3.0 mm 30 mm 2.0 μm 100 Å On request
Agilent Technologies Original ZORBAX Reversed-Phase Silica/C8 21.0 mm 250 mm 7.0 μm 70 Å On request
SiliCYCLE SiliaChrom XDB1 C8 Reversed-Phase Silica/C8 4.6 mm 150 mm 5.0 μm 100 Å On request
GL Sciences Inertsil WP300 C8 Reversed-Phase Silica/C8 1.0 mm 75 mm 5.0 μm 300 Å On request
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