TR-010057

Mediterranea Latest Generation HPLC Column

Moreover, the mediterrane sea column has been designed to show an excellent retention of polar compounds in a 100% aqueous environment without the problems of unwanted interactions which inefficiently endcapped conventional packings produce. Packing chemistry based on the new MED technology, “multifunctional endcapping deactivated”, achieves levels of deactivation, resistance to extreme pH values and versatility in its chromatographic applications never reached by conventional or polar-embedded reverse phase packings.The MED technology has been rigorously developed to achieve the maximum reproducibility, with the objective that its chromatographic separations will be, column to column, exactly the same.

An essential condition for obtaining the global-best reverse phase packing is an extremely pure silica. The silica particle, on which the new mediterranea sea packing is based, is obtained from ultra-pure materials, using rigorously controlled manufacturing processes to ensure that the slightest possibility of contamination is avoided. The mediterranea sea silica required intensive optimisation of numerous processing factors to achieve a perfectly spherical, rigid and inert particle possessing unusually low metal content. The almost total absence of metals is one of the pillars over which the extraordinary properties of the mediterranea sea column reside.