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A3050050X046
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Pursuit PFP

by Varian

Pursuit PFP: For Dipole Based Polar Separations

  • Unique fluorine based selectivity
  • Powerful resolution of positional isomers and halogenated compounds
  • High aqueous compatibility

The pentafluorophenyl ligand of Pursuit PFP provides an orthogonal separation mechanism to traditional reverse phase columns. By specifically targeting many polar retention mechanisms, Pursuit PFP can separate analytes based on small differences in structure, substitution, and steric access to polar moieties. The resulting selectivity for positional isomers, halogenated compounds, and polar analytes is particularly useful in the analysis of complex mixtures, and small molecule pharmaceuticals.

The 200Å pore structure of Pursuit PFP is particularly resistant to de-wetting phenomena or phase collapse. This, together with the polar retention mechanisms of PFP, allows the column to be used in high aqueous conditions, conditions ideal for the retention of highly polar analytes.

Application areas:
Pharmaceutical molecules Small molecules
Specification
Vendor Varian Pore size 200
Brand Pursuit PFP Surface Area 200
Modifification Silica/PFP Carbon Load, % 6.3
Mode Reversed-Phase Endcapped Yes
Particle Size pH stability from 3.0
Length pH stability to 7.5
Internal Diameter
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
Princeton Chromatography Inc. PrincetonSPHER PFP-60 Reversed-Phase Silica/PFP 30.0 mm 100 mm 10.0 μm 60 Å On request
Princeton Chromatography Inc. PrincetonSPHER PFP-60 Reversed-Phase Silica/PFP 4.6 mm 75 mm 3.0 μm 60 Å On request
Princeton Chromatography Inc. PrincetonSPHER PFP-100 Reversed-Phase Silica/PFP 4.6 mm 50 mm 5.0 μm 100 Å On request
Princeton Chromatography Inc. PrincetonSPHER PFP-60 Reversed-Phase Silica/PFP 4.6 mm 75 mm 5.0 μm 60 Å On request
Thermo Fisher Scientific Hypesil GOLD Reversed-Phase Silica/PFP 0.075 mm 100 mm 5.0 μm 175 Å On request
Vertical Chromatography VertiSep UPS PFP Reversed-Phase Silica/PFP 3.2 mm 150 mm 5 μm 100 Å On request
Thermo Fisher Scientific Hypesil GOLD Reversed-Phase Silica/PFP 0.5 mm 50 mm 3.0 μm 175 Å On request
Princeton Chromatography Inc. PrincetonSPHER PFP-60 Reversed-Phase Silica/PFP 21.2 mm 250 mm 10.0 μm 60 Å On request
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