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760078.3
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NUCLEODUR C18 GRAVITY

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features


NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C18 Gravity
High purity silica phase for HPLC
Nonpolar high density monomeric octadecyl modification,
endcapped · 18 % C · USP L1

Properties
 Key features:

  • Suitable for LC/MS and HPLC at pH extremes (pH 1–11)
  • Superior base deactivation
  • Ideal for method development

Technical characteristics:
High density octadecyl modification
Pore size 110 Å; particle sizes 1.8 μm, 3 μm and 5 μm
7, 10, 12 and 16 μm particles for preparative purposes on request
Carbon content 18 %
 Recommended application:
Overall sophisticated analytical separations
Compound classes separated include pharmaceuticals, e.g., analgesics, antiinflammatory drugs, antidepressants; herbicides; phytopharmaceuticals; immunosuppressants

Application areas:
Environmental samples Pharmaceutical molecules
Specification
Vendor MACHEREY-NAGEL Max Pressure 11600
Brand NUCLEODUR C18 GRAVITY Surface Area 340
Modifification Silica/C18 Carbon Load, % 18.0
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 1.0
Internal Diameter pH stability to 11.0
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
Varian Pursuit XRs C18 Reversed-Phase Silica/C18 4.0 mm 250 mm 5.0 μm 100 Å On request
Dionex Acclaim PepMap300 C18 Reversed-Phase Silica/C18 1.0 mm 50 mm 5.0 μm 300 Å On request
Merck Purospher® STAR Reversed-Phase Silica/C18 4.0 mm 30 mm 3.0 μm 120 Å On request
Sepax Technologies Sepax HP 120 C18 Reversed-Phase Silica/C18 0.5 mm 50 mm 5.0 μm 120 Å On request
Vertical Chromatography VertiSep AQS C18 Reversed-Phase Silica/C18 2.1 mm 150 mm 3.0 μm 120 Å On request
WATERS Atlantis T3 Reversed-Phase Silica/C18 3.0 mm 150 mm 5.0 μm 100 Å On request
MACHEREY-NAGEL NUCLEODUR C18 HTEC Reversed-Phase Silica/C18 4.0 mm 125 mm 5.0 μm 110 Å 410.00
Greyhound Spheripak ODS2 80 Reversed-Phase Silica/C18 4.6 mm 150 mm 3.0 μm 80 Å On request
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