760261.2

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

• totally spherical particle shape
• outstanding surface microstructure
• high pressure stability
• low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C18 Pyramid
High purity silica phase for HPLC
Octadecyl modification with polar endcapping,
suitable for aqueous eluents · endcapped · 14 % C · USP L1

Properties
 Key features:

• Stable in 100 % aqueous mobile phase systems
• Interesting polar selectivity features
• Excellent base deactivation; suitable for LC/MS due to low bleeding characteristics

Technical characteristics:
Special phase with polar endcapping
Pore size 110 Å; particle sizes 1.8 μm, 3 μm and 5 μm
7 and 10 μm particles for preparative purposes on request
Carbon content 14 %; pH stability 1–9
 Recommended application:
Analgesics, penicillin antibiotics, nucleic acid bases, water-soluble vitamins, complexing agents, organic acids