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760271.46
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NUCLEODUR C18 PYRAMID

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C18 Pyramid
High purity silica phase for HPLC
Octadecyl modification with polar endcapping,
suitable for aqueous eluents · endcapped · 14 % C · USP L1

Properties
 Key features:

  • Stable in 100 % aqueous mobile phase systems
  • Interesting polar selectivity features
  • Excellent base deactivation; suitable for LC/MS due to low bleeding characteristics

Technical characteristics:
Special phase with polar endcapping
Pore size 110 Å; particle sizes 1.8 μm, 3 μm and 5 μm
7 and 10 μm particles for preparative purposes on request
Carbon content 14 %; pH stability 1–9
 Recommended application:
Analgesics, penicillin antibiotics, nucleic acid bases, water-soluble vitamins, complexing agents, organic acids

Application areas:
DNA fragments Organic acids Pharmaceutical molecules Vitamins
Specification
Vendor MACHEREY-NAGEL Max Pressure 8700
Brand NUCLEODUR C18 PYRAMID Surface Area 340
Modifification Silica/C18 Carbon Load, % 14.0
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 1.0
Internal Diameter pH stability to 9.0
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
GRACE VisionHT C18 Polar Reversed-Phase Silica/C18 3.0 mm 250 mm 5.0 μm 100 Å On request
Reversed-Phase Silica/C18 3.0 mm 200 mm 10 μm 120 Å On request
Imtakt Cadenza CD-C18 Reversed-Phase Silica/C18 1.0 mm 50 mm 3.0 μm 120 Å On request
Altmann Analytik µBondapak C18 Reversed-Phase Silica/C18 4.0 mm 75 mm 10.0 μm 120 Å On request
Phenomenex Synergi Hydro-RP Reversed-Phase Silica/C18 0.075 mm 150 mm 4.0 μm 80 Å On request
Sepax Technologies Sepax HP 100 C18(2) Reversed-Phase Silica/C18 2.1 mm 250 mm 3.0 μm 100 Å On request
BISCHOFF ProntoSIL 120-5-C18 H Reversed-Phase Silica/C18 3.0 mm 300 mm 5.0 μm 120 Å On request
Agilent Technologies Original ZORBAX Reversed-Phase Silica/C18 9.0 mm 250 mm 5.0 μm 80 Å On request
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