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760272.4
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NUCLEODUR C18 PYRAMID

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C18 Pyramid
High purity silica phase for HPLC
Octadecyl modification with polar endcapping,
suitable for aqueous eluents · endcapped · 14 % C · USP L1

Properties
 Key features:

  • Stable in 100 % aqueous mobile phase systems
  • Interesting polar selectivity features
  • Excellent base deactivation; suitable for LC/MS due to low bleeding characteristics

Technical characteristics:
Special phase with polar endcapping
Pore size 110 Å; particle sizes 1.8 μm, 3 μm and 5 μm
7 and 10 μm particles for preparative purposes on request
Carbon content 14 %; pH stability 1–9
 Recommended application:
Analgesics, penicillin antibiotics, nucleic acid bases, water-soluble vitamins, complexing agents, organic acids

Application areas:
DNA fragments Organic acids Pharmaceutical molecules Vitamins
Specification
Vendor MACHEREY-NAGEL pH stability from 1.0
Brand NUCLEODUR C18 PYRAMID pH stability to 9.0
Modifification Silica/C18 Max Pressure 8700
Mode Reversed-Phase Surface Area 340
Particle Size Carbon Load, % 14.0
Length Endcapped Yes
Internal Diameter Operating Temperature 60
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
Agilent Technologies Agilent Polaris Reversed-Phase Silica/C18 3.0 mm 250 mm 5.0 μm 180 Å On request
Thermo Fisher Scientific Hypurity Reversed-Phase Silica/C18 4.0 mm 50 mm 5.0 μm 190 Å On request
Thermo Fisher Scientific Hypesil GOLD Reversed-Phase Silica/C18 50.0 mm 100 mm 12.0 μm 175 Å On request
KNAUER Eurospher II Reversed-Phase Silica/C18 4.0 mm 50 mm 5.0 μm 100 Å On request
Teknokroma Hyperpack ODS Reversed-Phase Silica/C18 3.0 mm 250 mm 5.0 μm On request
Higgins Analytical TARGA C18 Reversed-Phase Silica/C18 4.0 mm 150 mm 5.0 μm 120 Å On request
AcuTech Scientific C18 Reversed-Phase Silica/C18 0.32 mm 1000 mm 5.0 μm 120 Å On request
BISCHOFF ProntoSIL 200-3-C18 H Reversed-Phase Silica/C18 4.6 mm 100 mm 3.0 μm 200 Å On request
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