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760321.3
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NUCLEODUR C18 HTEC

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C18 HTec - High purity silica phase for preparative HPLC
Nonpolar high density monomeric octadecyl modification with high capacity · endcapped · 18 % C · USP L1
 
Properties
 Key features:

  • Reliable and durable standard RP phase for up-scaling to preparative scale, suited for LC/MS
  • High loadability and excellent stability
  • Outstanding base deactivation

Technical characteristics:
High density octadecyl modification
Pore size 110 Å; particle sizes 1.8 µm, 3 µm, 5 μm, 7 μm and 10 μm for analytical and preparative separations
Carbon content 18 %, pH stability 1–11
 Recommended application:
Sophisticated analytical and preparative separations of basic, neutral and acidic pharmaceuticals, derivatised amino acids, pesticides, fat-soluble vitamins, aldehydes, ketones and phenolic compounds

Application areas:
Acidic compounds Amino acids Basic compounds Environmental samples Neutral compounds Pharmaceutical molecules Vitamins
Specification
Vendor MACHEREY-NAGEL pH stability from 1.0
Brand NUCLEODUR C18 HTEC pH stability to 11.0
Modifification Silica/C18 Max Pressure 8700
Mode Reversed-Phase Surface Area 340
Particle Size Carbon Load, % 18.0
Length Endcapped Yes
Internal Diameter Operating Temperature 60
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
MACHEREY-NAGEL NUCLEODUR POLARTEC Reversed-Phase Silica/C18 4.6 mm 75 mm 5.0 μm 110 Å 384.00
GL Sciences Inertsil WP300 C18 Reversed-Phase Silica/C18 3.0 mm 30 mm 5.0 μm 300 Å On request
Higgins Analytical PHALANX C18 Reversed-Phase Silica/C18 0.3 mm 30 mm 3.0 μm 100 Å On request
BISCHOFF ProntoSIL 200-3-C18 ace-EPS Reversed-Phase Silica/C18 2.0 mm 200 mm 3.0 μm 200 Å On request
BISCHOFF ProntoSIL Spheribond ODS2 Reversed-Phase Silica/C18 2.0 mm 125 mm 10.0 μm 80 Å On request
Higgins Analytical PHALANX C18 Reversed-Phase Silica/C18 0.5 mm 100 mm 3.0 μm 100 Å On request
Orochem Matrix C18 Reversed-Phase Silica/C18 4.6 mm 100 mm 3.0 μm 100 Å On request
GL Sciences Inertsil ODS-2 Reversed-Phase Silica/C18 4.0 mm 150 mm 5.0 μm 150 Å On request
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