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760325.3
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NUCLEODUR C18 HTEC

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C18 HTec - High purity silica phase for preparative HPLC
Nonpolar high density monomeric octadecyl modification with high capacity · endcapped · 18 % C · USP L1
 
Properties
 Key features:

  • Reliable and durable standard RP phase for up-scaling to preparative scale, suited for LC/MS
  • High loadability and excellent stability
  • Outstanding base deactivation

Technical characteristics:
High density octadecyl modification
Pore size 110 Å; particle sizes 1.8 µm, 3 µm, 5 μm, 7 μm and 10 μm for analytical and preparative separations
Carbon content 18 %, pH stability 1–11
 Recommended application:
Sophisticated analytical and preparative separations of basic, neutral and acidic pharmaceuticals, derivatised amino acids, pesticides, fat-soluble vitamins, aldehydes, ketones and phenolic compounds

Application areas:
Acidic compounds Amino acids Basic compounds Environmental samples Neutral compounds Pharmaceutical molecules Vitamins
Specification
Vendor MACHEREY-NAGEL Max Pressure 8700
Brand NUCLEODUR C18 HTEC Surface Area 340
Modifification Silica/C18 Carbon Load, % 18.0
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 1.0
Internal Diameter pH stability to 11.0
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
Agilent Technologies Agilent Polaris Reversed-Phase Silica/C18 2.0 mm 250 mm 5.0 μm 180 Å On request
Sepax Technologies Sepax Bio 300 C18 Reversed-Phase Silica/C18 0.5 mm 50 mm 3.0 μm 300 Å On request
Vertical Chromatography VertiSep BIO C18 Reversed-Phase Silica/C18 30.0 mm 150 mm 10.0 μm 300 Å On request
Imtakt Cadenza 5CW-C18 Reversed-Phase Silica/C18 2.0 mm 30 mm 5.0 μm 300 Å On request
Imtakt Cadenza 5CD-C18 Reversed-Phase Silica/C18 1.0 mm 50 mm 5.0 μm 120 Å On request
ACE ACE UltraCore 2.5 Super C18 Reversed-Phase Silica/C18 4.6 mm 125 mm 2.5 μm 95 Å On request
Orochem Prestige C18 Reversed-Phase Silica/C18 2.0 mm 150 mm 5.0 μm 100 Å On request
Higgins Analytical PROTO 300 C18 Reversed-Phase Silica/C18 10.0 mm 50 mm 10.0 μm 300 Å On request
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