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760551.4
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NUCLEODUR HILIC

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® HILIC
High purity silica phase for Hydrophilic Interaction LIquid Chromatography


Properties
 Key features:

  • Ideal for reproducible and stable chromatography of highly polar analytes
  • Suitable for analytical and preparative applications as well as LC-MS
  • Very short column conditioning period  

Technical characteristics:
Ammonium – sulfonic acid modified silica: pore size 110 Å, available particle sizes 1.8 µm, 3 µm and 5 µm; carbon content 7 %;
pH stability 2–8.5
 Recommended application:
Hydrophilic compounds such as organic polar acids and bases, polar natural compounds, nucleosides, oligonucleotides, amino acids, peptides, water soluble vitamins

Application areas:
Amino acids Neutral compounds Nucleosides Oligonucleotides Organic acids Peptides Vitamins
Specification
Vendor MACHEREY-NAGEL Max Pressure 8700
Brand NUCLEODUR HILIC Surface Area 340
Modifification Ammonia/ Sulfonic acid Carbon Load, % 7.0
Mode HILIC Endcapped N/A
Particle Size Operating Temperature 60
Length pH stability from 2.0
Internal Diameter pH stability to 8.5
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
KNAUER Eurospher II HILIC Ammonia/ Sulfonic acid 8.0 mm 300 mm 5.0 μm 100 Å On request
KNAUER Eurospher II HILIC Ammonia/ Sulfonic acid 4.0 mm 125 mm 3.0 μm 100 Å On request
KNAUER Eurospher II HILIC Ammonia/ Sulfonic acid 4.0 mm 30 mm 5.0 μm 100 Å On request
MACHEREY-NAGEL NUCLEODUR HILIC HILIC Ammonia/ Sulfonic acid 2.0 mm 250 mm 5.0 μm 110 Å 465.00
KNAUER Eurospher II HILIC Ammonia/ Sulfonic acid 3.0 mm 50 mm 5.0 μm 100 Å On request
KNAUER Eurospher II HILIC Ammonia/ Sulfonic acid 4.6 mm 125 mm 5.0 μm 100 Å On request
KNAUER Eurospher II HILIC Ammonia/ Sulfonic acid 4.0 mm 300 mm 5.0 μm 100 Å On request
KNAUER Eurospher II HILIC Ammonia/ Sulfonic acid 4.6 mm 250 mm 5.0 μm 100 Å On request
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