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760754.46
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NUCLEODUR C8 GRAVITY

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC
Features
 NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C8 Gravity  
High purity silica phase for HPLC
Nonpolar high density monomeric octyl modification
endcapped · 11 % C · USP L7

Properties
 Key features:

  • Suitable for LC/MS and HPLC at pH extremes (pH 1–11)
  • Superior base deactivation
  • Ideal for method development  

 Technical characteristics:
High density octyl modification (C8)
Pore size 110 Å; particle sizes 1.8 and 5 μm
7, 10, 12 and 16 μm particles for preparative purposes on request
Carbon content 11 %
 Recommended application:
Overall sophisticated analytical separations
Compound classes separated include pharmaceuticals, e.g., analgesics, antiinflammatory drugs, antidepressants; herbicides, phytopharmaceuticals, immunosuppressants

Application areas:
Environmental samples Pharmaceutical molecules
Specification
Vendor MACHEREY-NAGEL Max Pressure 8700
Brand NUCLEODUR C8 GRAVITY Surface Area 340
Modifification Silica/C8 Carbon Load, % 11.0
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 1.0
Internal Diameter pH stability to 11.0
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
Bonna-Agela Technologies Durashell C8 Reversed-Phase Silica/C8 30.0 mm 100 mm 5.0 μm 100 Å On request
WATERS SunFire C8 Reversed-Phase Silica/C8 4.6 mm 100 mm 5.0 μm 100 Å On request
Princeton Chromatography Inc. PrincetonSPHER C8-100 Reversed-Phase Silica/C8 10.0 mm 150 mm 5.0 μm 100 Å On request
Chromenta Chromenta KB C8 Reversed-Phase Silica/C8 4.6 mm 100 mm 5.0 μm 120 Å On request
GL Sciences Inertsil C8-4 Reversed-Phase Silica/C8 2.1 mm 100 mm 3.0 μm 100 Å On request
Sepax Technologies Sepax GP 120 C8 Reversed-Phase Silica/C8 0.75 mm 150 mm 3.0 μm 120 Å On request
Thermo Fisher Scientific Hypurity Reversed-Phase Silica/C8 3.0 mm 120 mm 3.0 μm 190 Å On request
Agilent Technologies Agilent Polaris Reversed-Phase Silica/C8 2.0 mm 150 mm 3.0 μm 180 Å On request
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