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760755.3
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NUCLEODUR C8 GRAVITY

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC
Features
 NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C8 Gravity  
High purity silica phase for HPLC
Nonpolar high density monomeric octyl modification
endcapped · 11 % C · USP L7

Properties
 Key features:

  • Suitable for LC/MS and HPLC at pH extremes (pH 1–11)
  • Superior base deactivation
  • Ideal for method development  

 Technical characteristics:
High density octyl modification (C8)
Pore size 110 Å; particle sizes 1.8 and 5 μm
7, 10, 12 and 16 μm particles for preparative purposes on request
Carbon content 11 %
 Recommended application:
Overall sophisticated analytical separations
Compound classes separated include pharmaceuticals, e.g., analgesics, antiinflammatory drugs, antidepressants; herbicides, phytopharmaceuticals, immunosuppressants

Application areas:
Environmental samples Pharmaceutical molecules
Specification
Vendor MACHEREY-NAGEL pH stability from 1.0
Brand NUCLEODUR C8 GRAVITY pH stability to 11.0
Modifification Silica/C8 Max Pressure 11600
Mode Reversed-Phase Surface Area 340
Particle Size Carbon Load, % 11.0
Length Endcapped Yes
Internal Diameter Operating Temperature 60
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
Chromenta Chromenta BB C8 Reversed-Phase Silica/C8 4.0 mm 33 mm 3.0 μm 300 Å On request
Princeton Chromatography Inc. PrincetonSPHER C8-60 Reversed-Phase Silica/C8 4.0 mm 150 mm 10.0 μm 60 Å On request
LabHut Cronusil-L C8 Reversed-Phase Silica/C8 4.0 mm 150 mm 5.0 μm 120 Å 206.57
Thermo Fisher Scientific Acclaim Reversed-Phase Silica/C8 3.0 mm 50 mm 2.2 μm 120 Å On request
SGE Analytical Science ProteCol C8 H (PEEK Coated) Reversed-Phase Silica/C8 3.0 mm 150 mm 5.0 μm 120 Å On request
Sigma Aldrich Discovery BIO Wide Pore C8 Reversed-Phase Silica/C8 21.2 mm 250 mm 10.0 μm 300 Å On request
Hitachi High-Technologies Hitachi LaChrom C8 Reversed-Phase Silica/C8 4.6 mm 250 mm 5.0 μm 120 Å On request
GL Sciences Inertsil C8-4 HP Reversed-Phase Silica/C8 2.1 mm 75 mm 3.0 μm 100 Å On request
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