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760802.4
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NUCLEODUR SPHINX RP

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® Sphinx RP - High purity silica phase for HPLC
Bifunctional RP phase, balanced ratio of propylphenyl and C18 ligands
endcapped · 15 % C · USP L1 / L11

Properties
Key features:

  • Distinct selectivity based on well-balanced bifunctional surface coverage
  • Widens the scope for method development based on additional π-π interactions
  • Suitable for LC/MS due to low bleeding characteristics

Technical characteristics:
Octadecyl and propylphenyl modified silica
pore size 110 Å; particle sizes 1.8 μm, 3 μm and 5 μm
carbon content 15 %; pH stability 1–10;
high reproducibility and consistent quality
 Recommended application:
Quinolone antibiotics, sulfonamides, xanthines, substituted aromatics

Application areas:
Aromatic compounds Bio-molecules Pharmaceutical molecules
Specification
Vendor MACHEREY-NAGEL Max Pressure 8700
Brand NUCLEODUR SPHINX RP Surface Area 340
Modifification Silica/C18/Phenyl Carbon Load, % 15.0
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 1.0
Internal Diameter pH stability to 10.0
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
ACE ACE C18-AR Reversed-Phase Silica/C18/Phenyl 3.0 mm 150 mm 3.0 μm 100 Å On request
ACE ACE C18-AR Reversed-Phase Silica/C18/Phenyl 3.0 mm 100 mm 5.0 μm 100 Å On request
ACE ACE C18-AR Reversed-Phase Silica/C18/Phenyl 1.0 mm 30 mm 3.0 μm 100 Å On request
ACE ACE C18-AR Reversed-Phase Silica/C18/Phenyl 10.0 mm 150 mm 5.0 μm 100 Å On request
ACE ACE Excel C18-AR Reversed-Phase Silica/C18/Phenyl 3.0 mm 150 mm 2.0 μm 100 Å On request
ACE ACE C18-AR Reversed-Phase Silica/C18/Phenyl 1.0 mm 50 mm 3.0 μm 100 Å On request
SiliCYCLE SiliaChrom Phenyl C18 Reversed-Phase Silica/C18/Phenyl 2.1 mm 150 mm 5.0 μm 100 Å On request
ACE ACE C18-AR Reversed-Phase Silica/C18/Phenyl 10.0 mm 100 mm 5.0 μm 100 Å On request
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