by MACHEREY-NAGEL
NUCLEOSIL® standard silica phases for HPLC
Features
NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure
NUCLEOSIL® C4 - Butyl modified silica phases for HPLC
Medium density modification, endcapping · ~ 2 % C · USP L26
Features
Endcapped phases for RP and ion-pairing chromatography
Available pore sizes 120, 300, 500, 1000 and 4000 Å, available particle sizes 5 µm, 7 µm and 10 µm
Separation mechanism based on hydrophobic (van der Waals) interactions, some residual silanol interactions
Retention times are shorter than on C8 and C18 phases
pH stability at 20 °C: 2–8
| Vendor | MACHEREY-NAGEL | Max Pressure | 5800 |
| Brand | NUCLEOSIL C4 | Surface Area | 200 |
| Modifification | Silica/C4 | Carbon Load, % | 4.0 |
| Mode | Reversed-Phase | Endcapped | Yes |
| Particle Size | Operating Temperature | 60 | |
| Length | pH stability from | 2.0 | |
| Internal Diameter | pH stability to | 8.0 | |
| Pore size | 120 |
| Vendor | Brand | Mode | Modification | Int. diam. | Length | Particles | Pores | Price |
|---|---|---|---|---|---|---|---|---|
| Thermo Fisher Scientific | BioBasic | Reversed-Phase | Silica/C4 | 4.6 mm | 150 mm | 5.0 μm | 300 Å | On request |
| LabHut | Cronusil-L C4 | Reversed-Phase | Silica/C4 | 2.1 mm | 200 mm | 3.0 μm | 120 Å | 286.33 |
| Luknova | Poro C4-300 | Reversed-Phase | Silica/C4 | 2.1 mm | 100 mm | 3.0 μm | 300 Å | On request |
| Princeton Chromatography Inc. | PrincetonSPHER C4-100 | Reversed-Phase | Silica/C4 | 4.6 mm | 150 mm | 5.0 μm | 100 Å | On request |
| KNAUER | Eurospher II | Reversed-Phase | Silica/C4 | 2.0 mm | 150 mm | 3.0 μm | 100 Å | On request |
| Thermo Fisher Scientific | Accucore | Reversed-Phase | Silica/C4 | 2.1 mm | 100 mm | 2.6 μm | 150 Å | On request |
| Luknova | Poro C4-300 | Reversed-Phase | Silica/C4 | 10.0 mm | 150 mm | 5.0 μm | 300 Å | On request |
| Welch Materials | Ultisil XB-C4 | Reversed-Phase | Silica/C4 | 4.6 mm | 33 mm | 5.0 μm | 300 Å | On request |
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