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720195.4

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720195.4
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NUCLEOSIL C8 HD

by MACHEREY-NAGEL

NUCLEOSIL® standard silica phases for HPLC

Features

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure

  • Wide acceptance as routine packings for very different fields of chromatography
  • One of the first spherical silicas used in HPLC
  • Developed in the early seventies, it became a world-renowned HPLC packing
  • Still found in many analytical and preparative applications
  • An absolutely reliable choice in HPLC
  • The largest variety of modified HPLC silicas available on the market
     

NUCLEOSIL® C8 HD - Octyl modified high density silica phase for HPLC
Monomeric modification, endcapped · 13 % C · USP L7

Features

 Hydrophobic, nonpolar phase for RP chromatography, pore size 100 Å, particle sizes 5 µm
pH stability 2–8, carbon content 13 %,
recommended for separation of moderately to highly polar (water-soluble) compounds
Applications: steroids, nucleosides, cyclodextrins, pharmacological plant constituents
Separation mechanism based on hydrophobic (van der Waals) interactions

Application areas:
Moderately polar compounds Nucleosides Pharmaceutical molecules Polar compounds Steroids
Specification
Vendor MACHEREY-NAGEL Max Pressure 5800
Brand NUCLEOSIL C8 HD Surface Area 350
Modifification Silica/C8 Carbon Load, % 20.0
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 2.0
Internal Diameter pH stability to 9.0
Pore size 100
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
Imtakt Unison US-C8 Reversed-Phase Silica/C8 4.0 mm 250 mm 5.0 μm 130 Å On request
Teknokroma Mediterranea Sea8 Reversed-Phase Silica/C8 3.0 mm 200 mm 5.0 μm 100 Å On request
Welch Materials Ultisil XB-C8 Reversed-Phase Silica/C8 4.0 mm 300 mm 5.0 μm 120 Å On request
RSTech HECTOR-M C8 Reversed-Phase Silica/C8 10.0 mm 250 mm 10.0 μm 100 Å On request
Phenomenex Luna C8(2) Reversed-Phase Silica/C8 4.6 mm 150 mm 3.0 μm 100 Å On request
ACE ACE C8 Reversed-Phase Silica/C8 21.2 mm 75 mm 5.0 μm 100 Å On request
Thermo Fisher Scientific Accucore Reversed-Phase Silica/C8 2.1 mm 100 mm 2.6 μm 80 Å On request
Sepax Technologies Sepax GP 120 C8 Reversed-Phase Silica/C8 1.0 mm 50 mm 4.0 μm 120 Å On request
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