by MACHEREY-NAGEL
NUCLEOSIL® standard silica phases for HPLC
Features
NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure
NUCLEOSIL® C18 HD
Octadecyl modified High Density silica phase for HPLC
Monomeric modification, endcapped · USP L1
Features
Hydrophobic, nonpolar phase for RP chromatography
Pore size 100 Å, available particle sizes 3 µm and 5 µm
pH stability 2–9, carbon content 20 %
Suited for separation of basic compounds such as pharmaceuticals
Separation mechanism based on hydrophobic (van der Waals) interactions
| Vendor | MACHEREY-NAGEL | Max Pressure | 5800 |
| Brand | NUCLEOSIL C18 HD | Surface Area | 350 |
| Modifification | Silica/C18 | Carbon Load, % | 20.0 |
| Mode | Reversed-Phase | Endcapped | Yes |
| Particle Size | Operating Temperature | 60 | |
| Length | pH stability from | 2.0 | |
| Internal Diameter | pH stability to | 9.0 | |
| Pore size | 100 |
| Vendor | Brand | Mode | Modification | Int. diam. | Length | Particles | Pores | Price |
|---|---|---|---|---|---|---|---|---|
| PerkinElmer | Brownlee Validated C18 | Reversed-Phase | Silica/C18 | 4.6 mm | 200 mm | 5.0 μm | 100 Å | On request |
| KNAUER | Eurosil Bioselect | Reversed-Phase | Silica/C18 | 8.0 mm | 250 mm | 3.0 μm | 300 Å | On request |
| Imtakt | Cadenza CD-C18 HT | Reversed-Phase | Silica/C18 | 2.0 mm | 10 mm | 3.0 μm | 120 Å | On request |
| Dionex | Acclaim 120 C18 | Reversed-Phase | Silica/C18 | 1.0 mm | 150 mm | 3.0 μm | 120 Å | On request |
| PerkinElmer | Brownlee Analytical DB Aqueous C18 | Reversed-Phase | Silica/C18 | 4.6 mm | 30 mm | 3.0 μm | — | On request |
| MACHEREY-NAGEL | NUCLEOSIL C18 | Reversed-Phase | Silica/C18 | 4.0 mm | 125 mm | 5.0 μm | 120 Å | 213.00 |
| BISCHOFF | ProntoSIL 120-5-C18AQ | Reversed-Phase | Silica/C18 | 2.0 mm | 200 mm | 5.0 μm | 120 Å | On request |
| MicroSolv Technology Corporation | Cogent HPS C18 | Reversed-Phase | Silica/C18 | 4.6 mm | 75 mm | 5.0 μm | 120 Å | On request |
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