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720990.46

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720990.46
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NUCLEOSIL C8

by MACHEREY-NAGEL

NUCLEOSIL® standard silica phases for HPLC

Features

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure

  • Wide acceptance as routine packings for very different fields of chromatography
  • One of the first spherical silicas used in HPLC
  • Developed in the early seventies, it became a world-renowned HPLC packing
  • Still found in many analytical and preparative applications
  • An absolutely reliable choice in HPLC
  • The largest variety of modified HPLC silicas available on the market

NUCLEOSIL® standard C8 phases - Octyl modified silica phases for HPLC
C8: not encapped · USP L7

Features

Nonpolar phases for RP chromatography
NUCLEOSIL® C8:
Not endcapped, available pore sizes 100, 120, 300 and 500 Å,
available particle sizes 3 µm, 5 µm, 7 µm and 10 µm
Separation mechanism based on hydrophobic (van der Waals) interactions, noticeable silanol interactions
pH stability at 20 °C for both types: 2–8; carbon content depends on phase

Application areas:
Moderately polar compounds Nucleosides Pharmaceutical molecules Polar compounds Steroids
Specification
Vendor MACHEREY-NAGEL Max Pressure 5800
Brand NUCLEOSIL C8 Surface Area 350
Modifification Silica/C8 Carbon Load, % 8.5
Mode Reversed-Phase Endcapped No
Particle Size Operating Temperature 60
Length pH stability from 2.0
Internal Diameter pH stability to 8.0
Pore size 100
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
LabHut Cronusil-S C8 Reversed-Phase Silica/C8 2.1 mm 100 mm 5.0 μm 80 Å 169.55
GL Sciences Inertsil C8-3 Reversed-Phase Silica/C8 3.0 mm 150 mm 3.0 μm 100 Å On request
RESTEK Pinnacle DB Reversed-Phase Silica/C8 4.6 mm 30 mm 3.0 μm 140 Å On request
CHEMINDIA CHEMSIL-OCTYL-C8 Reversed-Phase Silica/C8 2.0 mm 250 mm 5.0 μm 100 Å On request
Welch Materials Topsil C8 Reversed-Phase Silica/C8 4.0 mm 200 mm 3.0 μm 150 Å On request
Agilent Technologies ZORBAX Eclipse Plus Reversed-Phase Silica/C8 4.0 mm 150 mm 3.5 μm 95 Å On request
RSTech HECTOR-M C8 Reversed-Phase Silica/C8 21.2 mm 100 mm 5.0 μm 100 Å On request
Bonna-Agela Technologies Venusil ASB C8 Reversed-Phase Silica/C8 2.1 mm 100 mm 5.0 μm 150 Å On request
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