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721712.4

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721712.4
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NUCLEOSIL C18

by MACHEREY-NAGEL

 

NUCLEOSIL® standard silica phases for HPLC

NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure 

  • Wide acceptance as routine packings for very different fields of chromatography
  • One of the first spherical silicas used in HPLC
  • Developed in the early seventies, it became a world-renowned HPLC packing
  • Still found in many analytical and preparative applications
  • An absolutely reliable choice in HPLC
  • The largest variety of modified HPLC silicas available on the market

NUCLEOSIL® standard C18 phases - Octadecyl modified silica phases for HPLC

Features:

  • Nonpolar, endcapped phases for RP chromatography
  • Available pore sizes 50, 100, 120, 300, 500, 1000 and 4000 Å
  • Available particle sizes 3 µm, 5 µm, 7 µm and 10 µm
  • pH stability at 20 °C: 2–8, carbon content depending on pore size (see table below)
  • Separation mechanism based on hydrophobic (van der Waals) interactions, slight residual silanol interactions 
Application areas:
Acidic compounds Basic compounds Neutral compounds
Specification
Vendor MACHEREY-NAGEL pH stability from 2.0
Brand NUCLEOSIL C18 pH stability to 8.0
Modifification Silica/C18 Max Pressure 5800
Mode Reversed-Phase Surface Area 200
Particle Size Carbon Load, % 11.0
Length Endcapped Yes
Internal Diameter Operating Temperature 60
Pore size 120
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
LabHut Cronusil-L ODS-B Reversed-Phase Silica/C18 2.1 mm 100 mm 3.0 μm 120 Å 245.50
Sepax Technologies Sepax HP 120 C18 Reversed-Phase Silica/C18 0.075 mm 100 mm 1.8 μm 120 Å On request
Luknova HighSelect C18-120 Reversed-Phase Silica/C18 30.0 mm 100 mm 5.0 μm 120 Å On request
ACE ACE C18-300 Reversed-Phase Silica/C18 3.0 mm 20 mm 3.0 μm 300 Å On request
GL Sciences Inertsil ODS-SP Reversed-Phase Silica/C18 4.6 mm 75 mm 3.0 μm 100 Å On request
KYA Technologies Corporation HiQ Sil C18W - 120 Reversed-Phase Silica/C18 4.0 mm 300 mm 3.0 μm 120 Å On request
Greyhound GenSphere ODS2 120 Reversed-Phase Silica/C18 4.6 mm 250 mm 5.0 μm 120 Å On request
Higgins Analytical CLIPEUS C18 Reversed-Phase Silica/C18 0.3 mm 150 mm 5.0 μm 120 Å On request
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