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721850.4
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NUCLEOSIL C18 HD

by MACHEREY-NAGEL

NUCLEOSIL® standard silica phases for HPLC

Features


NUCLEOSIL® is a family of totally porous spherical silicas with a very pure and uniform SiO2 structure

  • Wide acceptance as routine packings for very different fields of chromatography
  • One of the first spherical silicas used in HPLC
  • Developed in the early seventies, it became a world-renowned HPLC packing
  • Still found in many analytical and preparative applications
  • An absolutely reliable choice in HPLC
  • The largest variety of modified HPLC silicas available on the market
     

NUCLEOSIL® C18 HD
Octadecyl modified High Density silica phase for HPLC

Monomeric modification, endcapped · USP L1

Features

 Hydrophobic, nonpolar phase for RP chromatography
Pore size 100 Å, available particle sizes 3 µm and 5 µm
pH stability 2–9, carbon content 20 %
Suited for separation of basic compounds such as pharmaceuticals
Separation mechanism based on hydrophobic (van der Waals) interactions

Application areas:
Nucleosides Pharmaceutical molecules Polar compounds Steroids
Specification
Vendor MACHEREY-NAGEL Max Pressure 5800
Brand NUCLEOSIL C18 HD Surface Area 350
Modifification Silica/C18 Carbon Load, % 20.0
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 2.0
Internal Diameter pH stability to 9.0
Pore size 100
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
GL Sciences Inertsil ODS-4 Reversed-Phase Silica/C18 1.5 mm 150 mm 5.0 μm 100 Å On request
KNAUER Eurospher II Reversed-Phase Silica/C18 20.0 mm 150 mm 15.0 μm 100 Å On request
Advanced Materials Technology HALO C18 Reversed-Phase Silica/C18 4.6 mm 150 mm 5.0 μm 90 Å On request
Thermo Fisher Scientific Acclaim Reversed-Phase Silica/C18 1.0 mm 50 mm 5.0 μm 100 Å On request
GRACE Vydac TP C18 Reversed-Phase Silica/C18 2.1 mm 50 mm 5.0 μm 300 Å On request
RSTech HECTOR-W C18 Reversed-Phase Silica/C18 21.2 mm 70 mm 5.0 μm 300 Å On request
ACE ACE C18 Reversed-Phase Silica/C18 1.0 mm 50 mm 5.0 μm 100 Å On request
Sepax Technologies Sepax GP 120 C18 Reversed-Phase Silica/C18 2.1 mm 30 mm 2.2 μm 120 Å On request
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