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760050.2
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NUCLEODUR C18 EC

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C18 ec - High purity silica phase for HPLC
Medium density monomeric octadecyl modification
endcapped · 17.5 % C · USP L1

Properties
 Key features:

  • Ideal and reliable standard RP phase for daily routine analysis and up-scaling for preparative HPLC
  • Medium density octadecyl modification with exhaustive endcapping
  • Wide range of application areas  

Technical characteristics:
Pore size 110 Å; particle sizes 3 μm and 5 μm; 7 μm, 10 μm, 12 μm,
16 μm, 20 μm, 30 μm and 50 μm for preparative separations;
carbon content 17.5 %; pH stability 1–9, high reproducibility from lot to lot
 Recommended application:
Basic, neutral or acidic drugs; derivatized amino acids; pesticides;
fat-soluble vitamins; aldehydes and ketones; phenolic compounds

Application areas:
Acidic compounds Amino acids Basic compounds Environmental samples Neutral compounds Peptides Pharmaceutical molecules Proteins Vitamins
Specification
Vendor MACHEREY-NAGEL pH stability from 1.0
Brand NUCLEODUR C18 EC pH stability to 9.0
Modifification Silica/C18 Max Pressure 8700
Mode Reversed-Phase Surface Area 340
Particle Size Carbon Load, % 17.5
Length Endcapped Yes
Internal Diameter Operating Temperature 60
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
Biotage Resolux 120 C18 Reversed-Phase Silica/C18 3.2 mm 20 mm 4.5 μm 120 Å On request
MACHEREY-NAGEL NUCLEODUR C18 GRAVITY Reversed-Phase Silica/C18 4.0 mm 250 mm 5.0 μm 110 Å 462.00
GRACE Alltima HP C18 AQ Reversed-Phase Silica/C18 2.1 mm 250 mm 5.0 μm 100 Å On request
Higgins Analytical PROTO 300 C18 Reversed-Phase Silica/C18 1.0 mm 150 mm 5.0 μm 300 Å On request
GL Sciences Inertsil ODS-3 Reversed-Phase Silica/C18 2.0 mm 33 mm 5.0 μm 100 Å On request
Dionex Acclaim 120 C18 Reversed-Phase Silica/C18 0.3 mm 50 mm 3.0 μm 120 Å On request
ChromaNik Technologies Inc. Sunniest C18 Reversed-Phase Silica/C18 2.0 mm 250 mm 3.0 μm 120 Å On request
Unimicro Technologies Inc. Globalsil-120-5-ODS-AP Reversed-Phase Silica/C18 4.6 mm 250 mm 5.0 μm 120 Å On request
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