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760159.2

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760159.2
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NUCLEODUR CN-RP

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® CN / CN-RP
High purity silica phase for HPLC
Cyano (nitrile) modification for NP and RP separations · 7 % C · USP L10

Features
 Key features:

  • High retention capacity especially for very polar and unsaturated compounds
  • Multi-mode column (RP and NP) widens scope of selectivity
  • Stable against hydrolysis at low pH (working range pH 1-8)

Technical characteristics:
Cyanopropyl modified high purity silica; pore size 110 Å, particle sizes 3 µm and 5 µm; 7 % C; special endcapping
High reproducibility from lot to lot; different retention characteristics in comparison to C8 and C18
 Recommended application:
Tricyclic antidepressants, steroids, organic acids

Application areas:
Organic acids Pharmaceutical molecules
Specification
Vendor MACHEREY-NAGEL pH stability from 1.0
Brand NUCLEODUR CN-RP pH stability to 8.0
Modifification Silica/CN Max Pressure 8700
Mode Reversed-Phase Surface Area 340
Particle Size Carbon Load, % 7.0
Length Endcapped Yes
Internal Diameter Operating Temperature 60
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
KNAUER Eurospher II Reversed-Phase Silica/CN 2.0 mm 50 mm 10.0 μm 100 Å On request
Sigma Aldrich Discovery Cyano Reversed-Phase Silica/CN 4.6 mm 20 mm 5.0 μm 180 Å On request
LabHut Cronusil-L CN Reversed-Phase Silica/CN 10.0 mm 250 mm 5.0 μm 120 Å 1,006.29
KNAUER Eurospher II Reversed-Phase Silica/CN 4.0 mm 30 mm 10.0 μm 100 Å On request
WATERS Nova-Pak CN HP Reversed-Phase Silica/CN 3.9 mm 75 mm 4.0 μm 60 Å On request
Orochem Reliasil CN 90 Reversed-Phase Silica/CN 3.0 mm 100 mm 3.0 μm 90 Å On request
Thermo Fisher Scientific Hypurity Reversed-Phase Silica/CN 2.1 mm 100 mm 5.0 μm — On request
KNAUER Eurospher II Reversed-Phase Silica/CN 3.0 mm 150 mm 5.0 μm 100 Å On request
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