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760701.4
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NUCLEODUR C8 EC

by MACHEREY-NAGEL

NUCLEODUR® high purity silica phases for HPLC

Features

NUCLEODUR® is a fully synthetical type B silica (silica of 3rd generation) offering highly advanced physical properties:

  • totally spherical particle shape
  • outstanding surface microstructure
  • high pressure stability
  • low metal content

NUCLEODUR® as a state-of-the-art silica is the ideal base material for modern HPLC phases. It is the result of MACHEREY-NAGEL's pioneering research in chromatography for almost 50 years.
NUCLEODUR® with 1.8 µm particle size for increased separation efficiency

NUCLEODUR® C8 ec - High purity silica phase for HPLC
Medium density monomeric octyl modification
endcapped · 10.5 % C · USP L7

Properties
 Key features:

  • Ideal and reliable standard RP phase for daily routine analysis and up-scaling for preparative HPLC
  • Medium density octyl modification with exhaustive endcapping
  • Wide range of application areas  

Technical characteristics:
Pore size 110 Å; particle sizes 3 μm and 5 μm; 7 μm, 10 μm,
16 μm, 20 μm, and 50 μm for preparative separations on request;
carbon content 10.5 %; pH stability 1–9, high reproducibility from lot to lot
 Recommended application:
Basic, neutral or acidic drugs; derivatized amino acids; pesticides;
fat-soluble vitamins; aldehydes and ketones; phenolic compounds

Application areas:
Acidic compounds Basic compounds Environmental samples Neutral compounds Pharmaceutical molecules Vitamins
Specification
Vendor MACHEREY-NAGEL Max Pressure 8700
Brand NUCLEODUR C8 EC Surface Area 340
Modifification Silica/C8 Carbon Load, % 10.5
Mode Reversed-Phase Endcapped Yes
Particle Size Operating Temperature 60
Length pH stability from 1.0
Internal Diameter pH stability to 9.0
Pore size 110
Similar columns Columns with same mode & modification — across all brands
VendorBrandModeModification Int. diam.LengthParticlesPoresPrice
ACE ACE C8-300 Reversed-Phase Silica/C8 21.2 mm 150 mm 5.0 μm 300 Å On request
Vertical Chromatography VertiSep Integral C8 Reversed-Phase Silica/C8 4.6 mm 75 mm 2.6 μm 100 Å On request
BISCHOFF ProntoSIL 300-3-C8 SH Reversed-Phase Silica/C8 4.0 mm 250 mm 3.0 μm 300 Å On request
SGE Analytical Science ProteCol C8 H (PEEK Coated) Reversed-Phase Silica/C8 3.0 mm 50 mm 3.0 μm 1000 Å On request
ACE ACE C8 Reversed-Phase Silica/C8 1.0 mm 35 mm 3.0 μm 100 Å On request
GL Sciences Inertsil C8-4 Reversed-Phase Silica/C8 0.5 mm 150 mm 3.0 μm 100 Å On request
Orochem Prestige C8 Reversed-Phase Silica/C8 4.6 mm 30 mm 5.0 μm 100 Å On request
Imtakt Unison US-C8 Reversed-Phase Silica/C8 0.2 mm 50 mm 5.0 μm 130 Å On request
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